Pascal Ballet, Jean-François Abgrall, Vincent Rodin and
Jacques Tisseau.
Simulation of thrombin generation during plasmatic coagulation and
primary hemostasis.
SMC'00, IEEE International Conference on System, Man & Cybernetics,
volume 1, pages 131-136, Nashville (USA), 8-11 October 2000.
Abstract:
This paper describes a simulation of the platelet agglutination in a damaged
vein. This agglutination, called plasmatic coagulation, appears in the human
body and its malfunction involves dramatic diseases like thrombosis or
hemophilia. We designed an in-machina experimentation that is very difficult
to do in-vitro. The first aim of this simulation is to verify one of the
biological models of plasmatic coagulation and primary hemostasis.
The second one is to test different ways to regulate the thrombin production.
Then, we simulate a haemophilia like disease and one of its possible
treatments.
[doi:10.1109/ICSMC.2000.884977]
[Ballet00b.pdf]