Pascal Ballet, Jacques-Olivier Pers, Vincent Rodin and Jacques Tisseau.
A multi-agent system to simulate an apoptosis model of B-CD5 cells.
SMC'98, IEEE International Conference on Systems, Man and Cybernetics,
volume 2, pages 3799-3804, San Diego, CA (USA), 11-14 October 1998.
Abstract:
Simulations of immune mechanisms become more and more numerous and accurate.
The aim of immune simulations is to reproduce in-machina, in-vitro and in-vivo
experimentation. Then, it is then possible to test the cell models and the
consequences of their interactions. Thus, comparing the simulation results
with the experimentation results the validity of the model can be demonstrated.
A distributed and cooperative system can advantageously be modeled by a
multiagent system. With this approach, the abstraction needed to model these
phenomena is reduced. The immune system is included into highly cooperative
and distributed systems. Moreover, it is quite easy to add or remove entities
in the model and to improve their behaviors.
In this paper, we present a multiagent system that reproduces in-machina a
set of in-vitro experimentation on the apoptosis phenomena.
[doi:10.1109/ICSMC.1998.726679]
[Ballet98c.pdf]