Sébastien Tripodi, Pascal Ballet and Vincent Rodin.
Computational energetic model of morphogenesis based on multi-agent
Cellular Potts Model.
In Advances in Computational Biology, Book Series: Advances in Experimental
Medicine and Biology, Springer, volume 680, part VII,
chapter 76, pages 685-692, September 2010.
Abstract:
The Cellular Potts Model (CPM) is a cellular automaton (CA),
developed by Glazier and Graner in 1992, to model the morphogenesis.
In this model, the entities are the cells.
It has already been improved in many ways; however, a key point in
biological systems, not defined in CPM, is energetic exchange between
entities. We integrate this energetic concept inside the CPM.
We simulate a cell differentiation inside a growing cell tissue.
The results are the emergence of dynamic patterns coming from the
consumption and production of energy.
A model described by CA is less scalable than one described by a
multi-agent system (MAS). We have developed a MAS based on the CPM,
where a cell agent is implemented from the cell of CPM together with
several behaviours, in particular the consumption and production of
energy from the consumption of molecules.
Keywords:
Morphogenesis, Cellular potts model, Multi-agents systems.
[doi:10.1007/978-1-4419-5913-3_76]
[Tripodi10c.pdf]